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Mandragora
Also called Mandrakes
Mandragora is a plant genus belonging to the nightshade family (Solanaceae). Members of the genus are known as mandrakes. Between three and five species are placed in the genus. The one or two species found around the Mediterranean constitute the mandrake of ancient writers such as Dioscorides. Two or three further species are found eastwards into China. All are perennial herbaceous plants, with large tap roots and leaves in the form of a rosette. Individual flowers are bell-shaped, whitish through to violet, and followed by yellow or orange berries.
Like many members of the Solanaceae, species of Mandragora contain highly biologically active alkaloids that make the plants poisonous. Their roots in particular have a long use in traditional medicine. Mandrakes are involved in many myths and superstitions.
Like many members of the Solanaceae, species of Mandragora contain highly biologically active alkaloids, tropane alkaloids in particular. Hanuš et al. reviewed the phytochemistry of Mandragora species. More than 80 substances have been identified; their paper gives the detailed chemical structure of 37 of them. The different parts of the plant contain different proportions and concentrations of alkaloids, with the roots having the highest concentrations. Alkaloids present include atropine, apoatropine, belladonnine, cuscohygrine, hyoscyamine, scopolamine (hyoscine), 3α-tigloyloxytropane, and 3α,6β-ditigloyloxytropane. M. caulescens and M. turcomanica are also reported to contain anisodamine.
Clinical reports of the effects of consumption of plants described as M. autumnalis (M. offinarum sensu lato) include severe symptoms similar to those of atropine poisoning, including blurred vision, dilation of the pupils (mydriasis), dryness of the mouth, difficulty in urinating, dizziness, headache, vomiting, blushing, and a rapid heart rate (tachycardia).
Mandragora species have a long use in traditional medicine, extracts being used for their real or supposed aphrodisiac, hypnotic, emetic, purgative, sedative, and pain-killing effects. Tropane alkaloids are known to be effective as analgesics and anaesthetics, and can be used to increase circulation and dilate pupils, among other effects. Hyoscine and anisodamine are used medicinally in China. Continued use of M. autumnalis in folk medicine was reported in Sicily in 2014. M. caulescens (as M. chinghaiensis) has been listed as a Chinese medicinal plant needing conservation.
Mandrake · Himalayan Mandrake · Mandrake · Turkmenian Mandrake
Text excerpted from the Wikipedia article Mandragora (genus) by its contributors, under CC BY-SA 4.0; the excerpts are shared under the same licence.
