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Senna occidentalis
Also called Coffee Senna, Negro Coffee, Stinking Weed, Ant Bush, Arsenic Bush, Birds Beak, Bitter Root
Senna occidentalis, commonly known as coffee senna, styptic weed, or septicweed, is a species of flowering plant in the family Fabaceae and is native to the southern United States of America, Mexico and South America. It is a shrub with pinnate leaves, with three to seven pairs of broadly elliptic to egg-shaped leaflets, and yellow flowers arranged in groups of two to four, with six fertile stamens in each flower. It is an aggressive, pantropical weed.
Senna occidentalis seeds contain anthraquinones (AQs) such as Rhein, Emodin, Aloe-emodin, Chrysophanol, and Physcion, which have been linked to hepatomyoencephalopathy in children. The cytotoxicity of these AQs correlates with their binding affinity to serum albumin, with Rhein showing the highest toxicity and binding affinity. The plant is reported to be poisonous to cattle, because it contains a known toxic derivative of anthraquinone called emodin, and the seeds contain chrysarobin (1,8-dihydroxy-3-methyl-9-anthrone) and N-methylmorpholine. The plant also has some poisonous characteristics to humans if enough of it is taken. Emodin and Aloe-emodin exhibited strong binding affinities to DNA, which is associated with their high cytotoxic potential. Rhein was found to oxidize glutathione (GSH) significantly, contributing to its toxic effects, while Physcion and Chrysophanol showed minimal interactions with DNA, correlating with their lower toxicity.
Coffee senna is native to the southern United States of America, Mexico and South America, but is an aggressive, pantropical weed. In Australia it is widespread but scattered in the north of Western Australia, the Northern Territory, South Australia, Queensland and New South Wales.
Rainforest Cassia · Sprawling Cassia · Emperor's candlesticks · Alexandrian senna · Desertsenna · Silver senna · Flor de San Jose · Matara Tea · Pepper Leaf Senna · Senna barronfieldii · Twinleaf senna · Christmasbush
Text excerpted from the Wikipedia article Senna occidentalis by its contributors, under CC BY-SA 4.0; the excerpts are shared under the same licence.
Life form, climate and native range: World Checklist of Vascular Plants, Royal Botanic Gardens, Kew (CC BY 3.0), reformatted; see Plants of the World Online.
